M. Ghandi, N. Zarezadeh, Abuzar Taheri
Mar 16, 2011
Citations
0
Influential Citations
26
Citations
Journal
Tetrahedron Letters
Abstract
Abstract 3-(2-Formyl-1 H -benzimidazol-1-yl)propanoic acid, as a bifunctional formyl acid was prepared in four steps. This compound underwent a one-pot reaction with amines and alkyl isocyanides via the Ugi 4-center-3-component condensation. A series of novel benzimidazole-fused 1,4-diazepine-5-ones were obtained via this method in moderate to excellent yields.