Lena Trifonov, Katerina Chumin, R. Gvirtz
Nov 1, 2020
Citations
0
Influential Citations
3
Citations
Journal
Mendeleev Communications
Abstract
Novel polyfunctional arenesulfonamides as potential fungicides were prepared in eight steps from 3-amino-5-bromobenzoic acid. Among them, methyl 3-bromo-2-nitro-5-(N-phenylsulfamoyl)benzoate exhibiting significant cytotoxic activity against Malassezia furfur is proposed as a lead for the development of drug candidates against skin diseases caused by the fungi, especially against seborrheic dermatitis.