Florence Lederer, J. Alix, Donal Hayes
Jul 25, 1977
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0
Influential Citations
31
Citations
Journal
Biochemical and biophysical research communications
Abstract
Summary We show in this paper that the unknown methylated aminoacid observed in E.coli ribosomal protein L11 is N-trimethylalanine. Using [3H]-alanine, we also observe the presence of N-monomethylalanine in 50S and 30S proteins whereas our previously published experiments had not detected the methylation of L33 and S11. A comparison of the relative amounts of monomethylalanine synthesized under various conditions leads us to suggest that an alternate methylation pathway, not involving S-adenosylmethionine, may exist for ribosomal proteins.