Jun Lu, Yinjuan Bai, Zhenjun Wang
Nov 18, 2000
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0
Influential Citations
222
Citations
Quality indicators
Journal
Tetrahedron Letters
Abstract
Abstract An efficient synthesis of 3,4-dihydropyrimidinones using lanthanum chloride heptahydrate as a catalyst from an aldehyde, β-keto ester and urea or thiourea in ethanol is described. Compared to the classical Biginelli reaction conditions, this new method consistently has the advantage of good yields (56–97%).