A. Couture*, E. Deniau, P. Grandclaudon
Jul 28, 1997
Citations
0
Influential Citations
62
Citations
Journal
Tetrahedron
Abstract
Abstract A series of 3-(alkyl and aryl)methylene-2,3-dihydro-1 H -isoindol-1-one derivatives was synthesized by a one-pot reaction sequence involving lithiation of 2- (or 3-)halogeno- N -phosphorylmethylbenzamides, cyclization of the aryne intermediate, metal migration and Horner reaction of the resulting phosphorylated aminocarbanion with selected aromatic and aliphatic aldehydes.