A. Ramazani, Yavar Ahmadi, R. Tarasi
2011
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0
Influential Citations
41
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Journal
Heteroatom Chemistry
Abstract
The iminium intermediate formed by the reaction of a secondary amine with acetaldehyde was reacted by (N-isocyanimino) triphenylphosphorane in the presence of an electron-poor (E)-cinnamic acid derivative to give the corresponding iminophosphorane intermediate, whose intramolecular the aza-Wittig reaction led to disubstituted 1,3,4-oxadiazole derivatives. The reactions were completed under neutral conditions at room temperature, and the corresponding disubstituted 1,3,4-oxadiazole derivatives were produced in excellent yields. © 2010 Wiley Periodicals, Inc. Heteroatom Chem 22:79–84, 2011; View this article online at wileyonlinelibrary.com. DOI 10.1002/hc.20660