M. Meziane, S. Royer, J. Bazureau
Feb 5, 2001
Citations
0
Influential Citations
15
Citations
Journal
Tetrahedron Letters
Abstract
Abstract Two simple and efficient ‘one-pot’ preparations of isoquinoline-3-carboxylates by domino reactions using phthalaldehydes and imidate (route A) or diethyl aminomalonate (route B) are described. The third route involves the use of ethyl glycinate, aminoacetonitrile and phthalaldehyde which yields the respective ethyl isoquinoline-3-carboxylate and isoquinoline-3-carbonitrile.