S. Sajadikhah, M. Maghsoodlou, N. Hazeri
Jun 1, 2012
Citations
0
Influential Citations
42
Citations
Journal
Monatshefte für Chemie - Chemical Monthly
Abstract
Abstractp-Toluenesulfonic acid monohydrate (p-TsOH·H2O) is a highly effective and efficient catalyst for the one-pot multicomponent coupling of aldehydes, amines, and β-ketoesters in EtOH at ambient temperature to give highly functionalized piperidines in high yields. This one-pot reaction has some important advantages such as the easy workup procedure, simple and readily available precursors, nontoxic and inexpensive catalyst, and good to high yields.Graphical abstract