H. Venkatesan, F. Hocutt, T. K. Jones
Apr 26, 2010
Citations
0
Influential Citations
35
Citations
Journal
The Journal of organic chemistry
Abstract
A straightforward and efficient one-step procedure for the synthesis of 2,4-unsubstituted quinoline-3-carboxylic acid ethyl esters is described. The simple reductive cyclization is carried out by treating various substituted o-nitrobenzaldehydes with inexpensive, commercially available 3,3-diethoxypropionic acid ethyl ester and SnCl(2).2H(2)O in refluxing ethanol.