Wen Huang, Q. Shen, Jialiang Wang
Jan 16, 2008
Citations
0
Influential Citations
69
Citations
Journal
The Journal of organic chemistry
Abstract
A mild, versatile, and efficient method for the one-step synthesis of substituted dihydro- and tetrahydroisoquinolines has been developed by the FeCl3.6H2O catalyzed intramolecular allenylation/cyclization reaction of benzylamino-substituted propargylic alcohols, representing the first example of the intramolecular Friedel-Crafts reaction of propargylic alcohols.