L. Shao, Sheng Chun-quan
2007
Citations
0
Influential Citations
1
Citations
Journal
The Journal of Pharmaceutical Practice
Abstract
Objective:To optimize the synthesis of econazole nitrate,a useful antifungal agent.Methods:Orthogonal experimen- tal design is used and the influence of temperature,catalyst,reaction time and solvent on the yield is investigated.Results:Solvent is more important than reaction time and catalyst.Conclusion:The new method has several advantages such as cheap reactants,facile reaction condition,convenient operation and high yield.