B. Lunelli
May 14, 2007
Citations
0
Influential Citations
13
Citations
Journal
Tetrahedron Letters
Abstract
1,2-Dichlorocyclobuten-3,4-dione, a key intermediate in the chemistry of cyclobutenes and their derivatives is obtained by the dimethylformamide catalyzed reaction of squaric acid and oxalyl chloride. The process was optimized by using guidelines from thermodynamics, transport properties, and experimental observations, and gives nearly quantitatively a product which can be easily brought to very high purity.