Optimum bifunctionality in a 2-(2-pyridyl-2-ol)-1,10-phenanthroline based ruthenium complex for transfer hydrogenation of ketones and nitriles: impact of the number of 2-hydroxypyridine fragments.

doi:10.1039/c6dt01961g

Paper

Optimum bifunctionality in a 2-(2-pyridyl-2-ol)-1,10-phenanthroline based ruthenium complex for transfer hydrogenation of ketones and nitriles: impact of the number of 2-hydroxypyridine fragments.

Published Jul 5, 2016 · Bhaskar Paul, K. Chakrabarti, Sabuj Kundu

Dalton transactions

Q1 SJR score

39

Citations

0

Influential Citations

Full textSemantic Scholar

Abstract

Considerable differences in reactivity and selectivity for 2-hydroxypyridine (2-HP) derived ruthenium complexes in transfer hydrogenation are described. Bifunctional Ru(ii)-(phenpy-OH) [phenpy-OH: 2-(2-pyridyl-2-ol)-1,10-phenanthroline] complex () exhibited excellent catalytic activity in transfer hydrogenation (TH) of ketones and nitriles. Notably, in comparison with all the reported 2-hydroxypyridine (2-HP) derived ruthenium complexes in transfer hydrogenation, complex displayed significantly higher activity. Additionally, exploiting the metal-ligand cooperativity in complex , chemoselective TH of ketones was achieved and sterically demanding ketones were readily reduced. An outer-sphere mechanism is proposed for this system as exogenous PPh3 has no significant effect on the rate of this reaction. This is a rare example of a highly active bifunctional Ru(ii) catalyst bearing only one 2-HP unit.

Study Snapshot

The bifunctional Ru(ii)-(phenpy-OH) complex demonstrates excellent catalytic activity in transfer hydrogenation of ketones and nitriles, with a unique outer-sphere mechanism proposed for sterically demanding ketones.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Sign up to use Study Snapshot

Consensus is limited without an account. Create an account or sign in to get more searches and use the Study Snapshot.

Create an account

Paper

Optimum bifunctionality in a 2-(2-pyridyl-2-ol)-1,10-phenanthroline based ruthenium complex for transfer hydrogenation of ketones and nitriles: impact of the number of 2-hydroxypyridine fragments.

Sign up to use Study Snapshot

References

Chemoselective transfer hydrogenation of α,β-unsaturated carbonyl compounds using potassium formate over amine-grafted Ru/AlO(OH) catalysts

The amine-grafted Ru/AlO(OH) catalyst effectively transfers hydrogenation of,-unsaturated carbonyl compounds to allylic alcohols with high selectivity, maintaining activity and chemoselectivity even after five cycles.

Transfer Hydrogenation of Nitriles, Olefins, and N-Heterocycles Catalyzed by an N-Heterocyclic Carbene-Supported Half-Sandwich Complex of Ruthenium

The N-heterocyclic carbene-supported half-sandwich complex of ruthenium catalyzes transfer hydrogenation of nitriles, activated N-heterocycles, olefins, and conjugated olefins in isopropan

Ruthenium complexes bearing an unsymmetrical pincer ligand with a 2-hydroxypyridylmethylene fragment: active catalysts for transfer hydrogenation of ketones.

Ruthenium complexes with 2-hydroxypyridylmethylene fragments show high catalytic activity for transfer hydrogenation of ketones, with intramolecular hydrogen-bonding between -OH groups.

Simple Ligand Modifications with Pendent OH Groups Dramatically Impact the Activity and Selectivity of Ruthenium Catalysts for Transfer Hydrogenation: The Importance of Alkali Metals

Pendent OH groups significantly impact the activity and selectivity of ruthenium catalysts for transfer hydrogenation, orienting substrates and modulating electronics at the metal center.

Details of the Mechanism of the Asymmetric Transfer Hydrogenation of Acetophenone Using the Amine(imine)diphosphine Iron Precatalyst: The Base Effect and The Enantiodetermining Step

The asymmetric transfer hydrogenation of acetophenone using the iron precatalyst (S,S)-trans-[FeCl(CO)(PPh2CH2CH2NHCHPhCHPhNCHCH2PAr2)]BPh4 shows a base effect and

Citations