M. Inchiosa
Feb 1, 1967
Citations
0
Influential Citations
19
Citations
Journal
Biochemical pharmacology
Abstract
Abstract An epinephrine-oxidizing enzyme from bovine uterine muscle has been further purified and characterized. Adrenochrome is an intermediate in the oxidation of epinephrine by this enzyme. Adrenochrome also activates the enzyme, resulting in an autocatalytic oxidation of epinephrine. Another product of this reaction, which has been isolated and tentatively identified as a zwitterion isomer of adrenochrome, strongly inhibits actomyosin ATPase.