Perspectives for the microbial production of ethyl acetate

doi:10.1007/s00253-020-10756-z

Paper

Perspectives for the microbial production of ethyl acetate

Published Jul 12, 2020 · Shangjie Zhang, Feng Guo, Wei Yan

Applied Microbiology and Biotechnology

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35

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1

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Abstract

Ethyl acetate is one of the short-chain esters and widely used in the food, beverage, and solvent areas. The ethyl acetate production currently proceeds through unsustainable and energy intensive processes, which are based on natural gas and crude oil. Microbial conversion of biomass-derived sugars into ethyl acetate may provide a sustainable alternative. In this review, the perspectives of bio-catalyzing ethanol and acetic acid to ethyl acetate using lipases in vitro was introduced. Besides, the crucial elements for high yield of ethyl acetate in fermentation was expounded. Also, metabolic engineering in yeasts to product ethyl acetate in vivo using alcohol acyl transferases (AAT) was discussed. •The accumulation of acetyl-CoA is crucial for synthesizing ethyl acetate in vivo; AAT-mediated metabolic engineering could efficiently improve ethyl acetate production.

Study Snapshot

Microbial conversion of biomass-derived sugars into ethyl acetate offers a sustainable alternative to current processes, with potential for use in food, beverage, and solvent industries.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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Perspectives for the microbial production of ethyl acetate

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Citations

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