G. Chen, B. Zeng, Sarah Eastmond
Nov 1, 2012
Citations
3
Influential Citations
42
Citations
Quality indicators
Journal
British Journal of Pharmacology
Abstract
BACKGROUND AND PURPOSE Fenamate analogues, econazole and 2‐aminoethoxydiphenyl borate (2‐APB) are inhibitors of transient receptor potential melastatin 2 (TRPM2) channels and are used as research tools. However, these compounds have different chemical structures and therapeutic applications. Here we have investigated the pharmacological profile of TRPM2 channels by application of newly synthesized fenamate analogues and the existing channel blockers.