THE PHARMACOLOGY OF 3-PHENOXYPROPYLGUANIDINE.

doi:10.1016/s0022-3565(25)26741-6

Paper

THE PHARMACOLOGY OF 3-PHENOXYPROPYLGUANIDINE.

Published Mar 1, 1964 · G. Chen, C. Ensor, D. Mccarthy

The Journal of pharmacology and experimental therapeutics

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6

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0

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Abstract

Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.

Non-RCT

Animal Study

Study Snapshot

Phenoxypropylguanidine is a catecholamine releasing agent with potential benefits for treating hypertension, reserpine-induced ptosis, and preventing reserpine-induced ptosis in mice.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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Paper

THE PHARMACOLOGY OF 3-PHENOXYPROPYLGUANIDINE.

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References

Citations

The antagonism of adrenergic neurone blockade by amphetamine and dexamphetamine in the rat and guinea‐pig

Amphetamine can restore contractile responses to sympathetic nerve stimulation in bretylium-treated rats and weakly antagonize guanethidine-treated animals.

The antihypertensive properties of 1-amino-4-phenyl pyridinium chloride.

The antihypertensive agent (1-amino-4-phenyl pyridinium chloride, AH.2035) shows promising effects on the autonomic nervous and cardiovascular systems, with potential applications in treating hypertension.

The action of adrenergic neurone blocking agents and other drugs on the pressor responses of various agents in the anaesthetized rat.

Adrenergic neurone blocking agents and other drugs can alter pressor responses to various agents in anaesthetized rats, potentially affecting sympathetic nerve transmission.

The chemistry of guanidines and their actions at adrenergic nerve endings.

Guanidine derivatives have been successful as antihypertensive drugs, lowering blood pressure by blocking sympathetic nerves.

Antihypertensive agents 1962-1968.

Antihypertensive agents have made steady progress since 1962, with new developments including reserpine, hydralazine, guanethidine, and chlorothiazide.