Protective Potential of Ginkgo biloba against an ADHD-like Condition.

doi:10.2174/1874467213666200424152454

Paper

Protective Potential of Ginkgo biloba against an ADHD-like Condition.

Published Apr 24, 2020 · G. Sharma, Naveen Sharma, B. Nguyen

Current molecular pharmacology

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7

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0

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Abstract

BACKGROUND Attention deficit hyperactivity disorder (ADHD) is a psychiatric disorder commonly found in children, which is recognized by hyperactivity and aggressive behavior. It is known that the pathophysiology of ADHD is associated with neurobiological dysfunction. Although psychostimulants are recognized as the therapeutic drugs of choice for ADHD patients, the side effects might be of great concern. Ginkgo biloba is a promising herbal complementary supplement that may modulate the neuronal system in an ADHD-like condition. The beneficial effect of Ginkgo biloba on ADHD-like symptoms may be related to the modulation of the system by novel molecular mechanisms. Ginkgo biloba is known to modulate dopamine, serotonin, and norepinephrine signaling. Flavonoid glycosides and terpene trilactones are the two major phytochemical components present in the Ginkgo biloba preparations, which can exhibit antioxidant and neuroprotective activities. The pharmacological mechanisms of the phytochemical components may also contribute to the neuroprotective activity of Ginkgo biloba. CONCLUSION In this review, we have summarized recent findings on the potential of various Ginkgo biloba preparations to treat ADHD-like symptoms. In addition, we have discussed the pharmacological mechanisms mediated by Ginkgo biloba against an ADHD-like condition.

Literature Review

Study Snapshot

Ginkgo biloba shows potential in treating ADHD-like symptoms through modulation of neuronal systems and neuroprotective activities.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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Protective Potential of Ginkgo biloba against an ADHD-like Condition.

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References

Citations

Ginkgo biloba and Its Chemical Components in the Management of Alzheimer's Disease.

Ginkgo biloba extracts show promising therapeutic effects on various neurodegenerative diseases, including Alzheimer's disease, with few adverse reactions.

Natural compounds efficacy in Ophthalmic Diseases: A new twist impacting ferroptosis.

Ferroptosis, a cell death mechanism, is closely related to various eye diseases, and natural compounds may be potential treatments for these diseases in the future.

Natural antioxidant formula ameliorates lipopolysaccharide-induced impairment of hippocampal neurogenesis and contextual fear memory through suppression of neuroinflammation in rats

A natural antioxidant formula (NAF) can improve hippocampal neurogenesis and fear memory learning in rats by suppressing neuroinflammation.

Effect of Ginkgo biloba extract on pharmacology and pharmacokinetics of atorvastatin in rats with hyperlipidaemia.

Ginkgo biloba extract combined with statins significantly improves blood lipid parameters, reduces liver fat content, and provides additional liver protection in treating hyperlipidaemia.

Phytotherapy for Attention Deficit Hyperactivity Disorder (ADHD): A Systematic Review and Meta-analysis

Herbal remedies like Melissa officinalis, Bacopa monnieri, Matricaria chamomilla, and Valeriana officinalis show potential in treating ADHD symptoms, but more research is needed to confirm their effectiveness and safety.