Masato Yoshida, Y. Morinaga, M. Iyoda
Jul 1, 1994
Citations
0
Influential Citations
18
Citations
Journal
Journal of Fluorine Chemistry
Abstract
Abstract A convenient route for the synthesis of difluoromethylene-functionalized compounds from chlorodifluoroacetic acid has been investigated. Bis(chlorodifluoroacetyl) peroxide, which was synthesized from chlorodifluoroacetic acid via its acid anhydride, was found to be a good reagent for the chlorodifluoromethylation of electron-rich aromatic compounds and olefins. The chlorine atom of the chlorodifluoromethylated compounds, thus prepared, exchanged hydrogen and allyl groups by reaction with tributyltin hydride and allyltributyltin, respectively, under radical conditions.