Paper
Preparation of enantiomerically enriched (S)-ethyl 3-hydroxy 4,4,4-trifluorobutanoate using whole cells of Candida parapsilosis ATCC 7330
Published 2015 · S. Venkataraman, A. Chadha
Journal of Fluorine Chemistry
Q3 SJR score
8
Citations
0
Influential Citations
Abstract
Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.
Study Snapshot
Candida parapsilosis ATCC 7330 can produce enantiomerically enriched (S)-ethyl 3-hydroxy 4,4,4-trifluorobutanoate using different strategies and optical purity.
PopulationOlder adults (50-71 years)
Sample size24
MethodsObservational
OutcomesBody Mass Index projections
ResultsSocial networks mitigate obesity in older groups.
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References
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Fluorine-containing drugs have been introduced to the pharmaceutical market in the last decade (2001-2011), with a focus on enhancing the effectiveness of existing drugs and developing new ones.
2014·3303citations·Jiang Wang et al.·Chemical reviews
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Asymmetric Reduction of Alkyl-3-oxobutanoates by Candida parapsilosis ATCC 7330: Insights into Solvent and Substrate Optimisation of the Biocatalytic Reaction
Candida parapsilosis ATCC 7330 effectively reduces alkyl-3-oxobutanoates to (S)-isoamyl-3-hydroxybutanoate with good yields and enantiomeric excess, making it a promising biocatalytic method for producing optically pure
2013·14citations·S. Venkataraman et al.·Applied Biochemistry and Biotechnology
Applied Biochemistry and Biotechnology
Enantioselective bioreduction of ethyl 4,4,4-trihalide-3-oxobutanoate by Kluyveromyces marxianus
Kluyveromyces marxianus resting cells effectively bioreduce ethyl 4,4,4-trifluoro-3-oxobutanoate and ethyl 4,4,4-trichloro-3-oxobutanoate with enantioselect
2013·8citations·S. S. Oliveira et al.·Tetrahedron Letters
Tetrahedron Letters
Stereospecific Reduction of Methyl o‐Chlorobenzoylformate at 300 g⋅L−1 without Additional Cofactor using a Carbonyl Reductase Mined from Candida glabrata
CgKR1 from Candida glabrata effectively reduces methyl o-chlorobenzoylformate to (R)-CMM with excellent stereoselectivity, enabling the practical production of clopidogrel intermediates without external cofactors.
2012·58citations·Hongmin Ma et al.·Advanced Synthesis & Catalysis
Advanced Synthesis & Catalysis
One-pot synthesis of enantiomerically pure 1, 2-diols: asymmetric reduction of aromatic α-oxoaldehydes catalysed by Candida parapsilosis ATCC 7330
A one-pot method for producing enantiomerically pure 1, 2-diols with high yields and enantiomeric excess has been developed using Candida parapsilosis ATCC 7330.
2011·26citations·Pula Mahajabeen et al.·Tetrahedron-asymmetry
Tetrahedron-asymmetry
Citations
Photobiocatalytic Platform for the Efficient Enantio-Divergent Synthesis of β-Fluoromethylated Ketones.
This study developed an ene-reductase-based photobiocatalytic platform for efficient synthesis of enantio-divergent -fluoromethylated chiral ketones, offering a general photobiocatalytic solution for diverse chiral ketones in pharmaceutical and a
2024·0citations·Yuan-Yang Guo et al.·Journal of the American Chemical Society
Journal of the American Chemical Society
Multigram synthesis of ethyl (S)-4-chloro-3-hydroxybutanoate in a monophasic aqueous system using a robust NADH-dependent alcohol dehydrogenase from Pseudomonas bacterium
Pseudomonas bacterium's NADH-dependent alcohol dehydrogenase effectively converts ethyl 4-chloroacetoacetate into ethyl (S)-CHBE with high optical purity, making it a promising tool for pharmaceutical industries.
2024·1citation·Xuecai Wei et al.·Molecular Catalysis
Molecular Catalysis
Direct observation of redox reactions in Candida parapsilosis ATCC 7330 by Confocal microscopic studies
Candida parapsilosis ATCC 7330 is a versatile biocatalyst for redox enzyme-mediated preparation of optically pure secondary alcohols, with large vacuoles and spontaneous reaction kinetics.
2016·2citations·S. Venkataraman et al.·Scientific Reports
Scientific Reports
Candida parapsilosis: A versatile biocatalyst for organic oxidation-reduction reactions.
Candida parapsilosis is a versatile biocatalyst for efficient organic transformations, generating chiral synthons and industrial chemicals.
2016·21citations·A. Chadha et al.·Bioorganic chemistry
Bioorganic chemistry
Chemoenzymatic Synthesis of an Enantiomerically Enriched Bicyclic Carbocycle Using Candida parapsilosis ATCC 7330 Mediated Enantioselective Hydrolysis
Enantiomerically enriched bicyclic alcohols can be synthesized using Candida parapsilosis ATCC 7330, a biocatalyst with high enantiomeric excess and conversion rates.
2015·1citation·T. Saravanan et al.·Informs Journal on Computing
Informs Journal on Computing
Candida parapsilosis ATCC 7330 mediated oxidation of aromatic (activated) primary alcohols to aldehydes
This green, simple, and high-yielding procedure enables the oxidation of aromatic primary alcohols to aldehydes using whole cells of Candida parapsilosis ATCC 7330 under mild conditions at 25°C.
2015·6citations·T. Sivakumari et al.·RSC Advances
RSC Advances
Enantio- & chemo-selective preparation of enantiomerically enriched aliphatic nitro alcohols using Candida parapsilosis ATCC 7330
Candida parapsilosis ATCC 7330 effectively reduces keto groups in nitro ketones, producing enantiomerically enriched nitro alkanols in less time than conventional methods.
2015·8citations·S. Venkataraman et al.·RSC Advances
RSC Advances