T. Vaijayanthi, A. Chadha
May 29, 2007
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Influential Citations
26
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Journal
Tetrahedron-asymmetry
Abstract
Abstract Deracemisation of racemic (3 E )-alkyl-4-(hetero-2-yl)-2-hydroxybut-3-enoates using Candida parapsilosis ATCC 7330 resulted in the formation of one enantiomer in high enantiomeric excess [up to >99% ee] and isolated yields [up to 79%]. The absolute configuration of the enantiomerically pure (3 E )-ethyl-4-(thiophene-2-yl)-2-hydroxybut-3-enoate as determined by 1 H NMR of the Mosher esters was found to be ( S ).