J. Wrobel, A. Dietrich
May 28, 1993
Citations
0
Influential Citations
53
Citations
Journal
Tetrahedron Letters
Abstract
Abstract N-t-BOC-L-(Phosphonodifluoromethyl)phenylalanine benzyl ester ( 1 ) was prepared in 5 steps from N-t-BOC-L-tyrosine benzyl eser O-triflate ( 4 ). Compound 1 was further converted to derivatives 2 and 3 which are potentially suitable for peptide synthesis. Analogs 1 - 3 are non-hydrolyzable mimetics of O-phosphotyrosine.