J. Elsworth, C. Willis
Mar 19, 2008
Citations
0
Influential Citations
65
Citations
Journal
Chemical communications
Abstract
Methyl (4E,7R)-7-hydroxyoctanoate was prepared in 71% yield from ethyl (R)-3-hydroxybutanoate and on reaction with a series of aldehydes in the presence of TMSOTf gave bicyclic oxygen heterocycles in good yields and with the creation of three new stereogenic centres in a single pot.