S. Aggarwal, A. Goyal, Rajwinder Kaur
Oct 12, 2020
Citations
0
Influential Citations
4
Citations
Journal
Research Journal of Pharmacy and Technology
Abstract
Five membered heterocyclic ring structures, oxadiazoles contain one oxygen and two nitrogen atoms. The synthesis of 1,2,4-oxadiazole involves conversion of cyanide to hydroxyl amine followed by 1,3-dipolar cycloaddition reaction to form a ringed structure. Ring also acts as bioisostere for carboxylic acid and carboxamide group. Further 1,2,4-oxadiazole derivatives have been evaluated for a wide range of medicinal applications.