Â. C. Pinto, A. Lapis, B. Silva
Sep 22, 2008
Citations
0
Influential Citations
55
Citations
Journal
Tetrahedron Letters
Abstract
An efficient method was developed for the preparation of isatin-3-oxime derivatives with Bronsted and/ or Lewis acids in imidazolium-based ionic liquids. Isatin-3-oxime bearing the electron donating methoxy group was equally obtained in good yields. The pronounced ionic liquid effect avoids the direct formation of isatin in the acidified media and the reaction leads exclusively to isatin-3-oxime derivatives.