Psycho-endocrine-immune response to mindfulness-based stress reduction in individuals infected with the human immunodeficiency virus: a quasiexperimental study.

doi:10.1089/107555303322524535

Paper

Psycho-endocrine-immune response to mindfulness-based stress reduction in individuals infected with the human immunodeficiency virus: a quasiexperimental study.

Published Oct 1, 2003 · F. Robinson, H. Mathews, L. Witek-Janusek

Journal of alternative and complementary medicine

Q1 SJR score

175

Citations

5

Influential Citations

Full textSemantic Scholar

Abstract

OBJECTIVES The purpose of this study was to examine the effects of a structured, 8-week, Mindfulness-Based Stress Reduction (MBSR) program on perceived stress, mood, endocrine function, immunity, and functional health outcomes in individuals infected with the human immunodeficiency virus (HIV). DESIGN This study used a quasiexperimental, nonrandomized design. METHODS Subjects were specifically recruited (nonrandom) for intervention (MBSR) or comparison group. Data were collected at pretest and post-test in the MBSR group and at matched times in the comparison group. t Tests where performed to determine within-group changes and between-group differences. RESULTS Natural killer cell activity and number increased significantly in the MBSR group compared to the comparison group. No significant changes or differences were found for psychological, endocrine, or functional health variables. CONCLUSIONS These results provide tentative evidence that MBSR may assist in improving immunity in individuals infected with HIV.

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Study Snapshot

Key takeawayMindfulness-Based Stress Reduction may improve immunity in individuals infected with HIV, but no significant changes were found in psychological, endocrine, or functional health variables.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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Psycho-endocrine-immune response to mindfulness-based stress reduction in individuals infected with the human immunodeficiency virus: a quasiexperimental study.

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References

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Psychoneuroimmunology research faces methodological challenges, requiring careful control of variables, appropriate measurement methods, and careful specimen handling and assay performance.

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Mindfulness meditation-based stress reduction program effectively reduces mood disturbance and stress symptoms in cancer outpatients across various cancer diagnoses, stages, and ages.

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Citations

Comprehensive Review of Chronic Stress Pathways and the Efficacy of Behavioral Stress Reduction Programs (BSRPs) in Managing Diseases

Behavioral Stress Reduction Programs (BSRPs) show potential in enhancing medical therapies and reversing disease progression, but more long-term, large-scale studies are needed to validate their effectiveness.

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Medieval monastic health conditions were better in Bermondsey Abbey than in Merton Priory, likely due to greater health-promoting effects of religiosity or isolation from the lay community.

The Impact of Mindfulness-Based Stress Reduction (MBSR) on Psychological Outcomes and Quality of Life in Patients With Lung Cancer: A Meta-Analysis

Mindfulness-based stress reduction (MBSR) positively impacts psychological states and quality of life in lung cancer patients, reducing cancer-related fatigue and enhancing positive psychological states.

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Mindfulness-based interventions can improve immune function and potentially impact somatic disorders by reducing inflammation and increasing CD4+ cells.

Attitudes toward a mindfulness-based intervention from African American women living with HIV: A qualitative study

African American women living with HIV show strong interest in mindfulness-based stress reduction, but the existing program needs tailoring to address challenges and barriers for attendance and completion.

Effect of Mindfulness‐Based Stress Reduction on dehydroepiandrosterone‐sulfate in adults with self‐reported stress. A randomized trial

Mindfulness-Based Stress Reduction significantly increases dehydroepiandrosterone-sulfate levels compared to a waiting list and local stress reduction program in adults with self-reported stress.