Alberto Coelho, E. Sotelo, E. Raviña
Mar 31, 2003
Citations
0
Influential Citations
49
Citations
Journal
Tetrahedron
Abstract
Several 6-phenyl-3(2H)-pyridazinones bearing different alkynyl groups at position 5 have been prepared by a palladium-catalysed Sonogashira cross-coupling reaction. An interesting base-promoted electronically permitted isomerization has been observed during the coupling of 1-phenyl-2-propyn-1-ol. This rearrangement afforded the E-chalcone 6 in excellent yield.