Pyridine derivatives as insecticides. Part 1: synthesis and toxicity of some pyridine derivatives against cowpea aphid, Aphis craccivora Koch (Homoptera: Aphididae).

doi:10.1021/jf503992y

Paper

Pyridine derivatives as insecticides. Part 1: synthesis and toxicity of some pyridine derivatives against cowpea aphid, Aphis craccivora Koch (Homoptera: Aphididae).

Published Oct 2, 2014 · E. A. Bakhite, Aly A. Abd-Ella, M. El-Sayed

Journal of agricultural and food chemistry

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65

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Abstract

Five pyridine derivatives, namely, N-morpholinium 7,7-dimethyl-3-cyano-4-(4'-nitrophenyl)-5-oxo-1,4,5,6,7,8-hexahydroquinoline-2-thiolate (1), sodium 5-acetyl-3-amino-4-(4'-methoxyphenyl)-6-methylthieno[2,3-b] pyridine-2-carboxylate (2), piperidinium 3,5-dicyano-2-oxo-4-spirocyclopentane-1,2,3,4-tetrahydropyridine-6-thiolate (3), piperidinium 5-acetyl-3-cyano-4-(4'-methoxyphenyl)-6-methylpyridine-2-thiolate (4), and piperidinium 5-acetyl-4-(4'-chlorophenyl)-3-cyano-6-methyl-pyridine-2-thiolate (5) were prepared in pure state and subjected to the title study. The bioassay results indicated that the insecticidal activity of compound 1 is about 4-fold that of acetamiprid insecticide. The rest of the tested compounds possess moderate to strong aphidicidal activities.

In Vitro Study

Study Snapshot

Pyridine derivatives show moderate to strong aphidicidal activities, with compound 1 showing a 4-fold activity increase over acetamiprid.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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Paper

Pyridine derivatives as insecticides. Part 1: synthesis and toxicity of some pyridine derivatives against cowpea aphid, Aphis craccivora Koch (Homoptera: Aphididae).

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Citations

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Thiazolidinedione-morpholine hybrid ionic liquids show potential as new antidiabetic agents, with compound 11 k showing the most potent reduction in blood glucose levels.

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This study developed an environmentally friendly one-pot method for the synthesis of 1,2,3,4-tetrahydropyridines and hexahydroimidazo[1,2-a]pyridines in water, with only three water molecules as by-products.

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New thieno[2,3-b]pyridines and pyrazolo[3,4-b]pyridines show promising insecticidal activity against Aphis gossypii, with sublethal concentrations affecting nymphal instar duration, generation time, and adult

Effects of pyriproxyfen on development and hormone of the aphis, Aphis craccivora (Hemiptera: Aphididae).

Pyriproxyfen effectively kills aphids and inhibits their reproductive ability, making it an effective control method for aphids.

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Novel pyridines 7 and 8 show promising insecticidal activity against cowpea aphids, offering eco-friendly, cost-effective, and eco-friendly solutions for pest control.

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Quinazoline derivatives (4a-l) show potential as insecticidal agents for crop protection, with compound (4b) showing the highest insecticidal activity and others showing good potential.

X-ray Diffraction, Spectroscopy, Optical Properties, NPA, NBO, FMO, and Hirshfeld Surface Analyses of Two Newly Synthesized Piperidinium Ionic Liquids

Two new piperidinium ionic liquids have been synthesized, with HH interactions being significantly higher than other element interactions in their crystal structures.

Pyridine Derivatives as Insecticides─Part 4: Synthesis, Crystal Structure, and Insecticidal Activity of Some New Thienylpyridines, Thienylthieno[2,3-b]pyridines, and Related Heterocyclic Derivatives.

New thienylpyridines and thienylthieno[2,3-b]pyridines show promising insecticidal activity against Aphis gossypi nymphs and adults, with crystal structures determined by X-ray diffraction.