Pyrroxamycin, a new antibiotic taxonomy, fermentation, isolation, structure determination and biological properties.

doi:10.7164/ANTIBIOTICS.40.961

Paper

Pyrroxamycin, a new antibiotic taxonomy, fermentation, isolation, structure determination and biological properties.

Published Jul 1, 1987 · K. Yano, J. Oono, K. Mogi

The Journal of antibiotics

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13

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0

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Abstract

A strain of streptomycete was found to produce a new antibiotic pyrroxamycin. This compound was isolated from the culture broth of Streptomyces sp. S46506. The chemical structure was determined to be 4,5-dichloro-2-(6',8'-dichloro-4'H-1',3'-benzodioxin-4'-yl)-3-nitr opyrrole by its chemical character and 1H and 13C NMR spectral analysis. Pyrroxamycin was active against Gram-positive bacteria and dermatophytes.

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Key takeawayPyrroxamycin, a new antibiotic from Streptomyces sp. S46506, shows activity against Gram-positive bacteria and dermatophytes.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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Pyrroxamycin, a new antibiotic taxonomy, fermentation, isolation, structure determination and biological properties.

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