J. Katze
Sep 1, 1985
Citations
0
Influential Citations
3
Citations
Journal
Proceedings of the Society for Experimental Biology and Medicine
Abstract
Abstract The observed enhancement of B-lymphocyte activation by 8-bromoguanosine and 8-mercaptoguanosine is hypothesized to occur via a “binding protein” which requires a guanine nucleoside as the syn conformer for productive interaction. In addition, because of the 7-substituent, Q nucleoside also is hypothesized to bind as the syn conformer and, therefore, to be a potential B-lymphocyte activator.