W. Wardakhan, N. A. Louca, M. Kamel
2007
Citations
0
Influential Citations
6
Citations
Journal
Acta Chimica Slovenica
Abstract
The reaction of 2-amino-tetrahydrobenzo[b]thiophene derivatives la-d with ethoxycarbonyl isothiocyanate (2) gave the tetrahydrobenzo[b]thiophen-2-thiourea derivatives 3a-d. The latter products underwent ready cyclizations when heated in sodium ethoxide solution to give annulated derivatives 4a-d. Compounds 3a-d also underwent hetero-cyclizations to give fused thiophene derivatives with antibacterial and antifungal activities.