C. R. Burkholder, W. Dolbier, M. Médebielle
Feb 3, 1997
Citations
0
Influential Citations
21
Citations
Journal
Tetrahedron Letters
Abstract
Abstract Tetrakis(dimethylamino)ethylene (TDAE) was found to be an effective reductant of the 2-(bromodifluoromethyl)benzoxazole 1 . The generated 2-(difluoromethyl) benzoxazole anion was trapped with several aldehydes 2 – 9 , under mild conditions, to give the corresponding 2-(difluoromethyl)benzoxazole alcohols 10 – 17 , in moderate to good yields.