V. Shvedov, V. K. Vasil'eva, A. Grinev
Jun 1, 1971
Citations
0
Influential Citations
3
Citations
Journal
Chemistry of Heterocyclic Compounds
Abstract
Abstract2-Methyl-3-ethoxycarbonyl-4-(N,N-dimethylhydrazino)thiophene (II) and 2-methyl-3-ethoxy-carbonyl-4-(N-phenylhydrazino)thiophene (III) are formed by the action of substituted hydrazines — N,N-dimethylhydrazine and phenylhydrazine — on 2-methyl-3-ethoxycarbonyl-4-hydroxythiophene (I). At the same time, the thiophene ring of hydroxythiophene I undergoes hydrazinolysis under the influence of hydrazine hydrate to form 3-mercaptomethyl-4-ethoxycarbonyl-5-methylpyrazole (IV). Structure IV was proved by IR, UV, and PMR spectroscopy and by hydrogenolysis of IV to the known 3,5-dimethyl-4-ethoxycarbonylpyrazole (V).