THE REACTION OF 3-METHYL-2-BUTENYL PHENYL SULFIDE WITH ALDEHYDES AND KETONES. APPLICATION TO THE SYNTHESIS OF 2,2-DIMETHYLCYCLOPROPANECARBALDEHYDES

doi:10.1246/CL.1974.1371

Paper

THE REACTION OF 3-METHYL-2-BUTENYL PHENYL SULFIDE WITH ALDEHYDES AND KETONES. APPLICATION TO THE SYNTHESIS OF 2,2-DIMETHYLCYCLOPROPANECARBALDEHYDES

Published Nov 5, 1974 · K. Kondo, K. Matsui, A. Negishi

Chemistry Letters

Q2 SJR score

1

Citations

0

Influential Citations

Full textSemantic Scholar

Abstract

The base promoted addition of 3-methyl-2-butenyl phenyl sulfide to aldehydes and ketones occurred selectively on the γ-position of the allylic moiety. The product was converted to the methanesulfonate. Treatment of the resulting homoallylic ester with nucleophiles induced the cyclization to give cyclopropane derivatives in excellent yields.

Study Snapshot

3-Methyl-2-Butenyl Phenyl SULFIDE selectively adds to aldehydes and ketones, resulting in the synthesis of 2,2-DIMETHYLCYCLOPROPANECARBALDEHYDES in excellent yields.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Sign up to use Study Snapshot

Consensus is limited without an account. Create an account or sign in to get more searches and use the Study Snapshot.

Create an account

THE REACTION OF 3-METHYL-2-BUTENYL PHENYL SULFIDE WITH ALDEHYDES AND KETONES. APPLICATION TO THE SYNTHESIS OF 2,2-DIMETHYLCYCLOPROPANECARBALDEHYDES

Sign up to use Study Snapshot

References

Citations