Reactions of 3,3,4,4-tetracyanopyrrolidines with alcohols

doi:10.1007/BF00532072

Paper

Reactions of 3,3,4,4-tetracyanopyrrolidines with alcohols

Published Nov 1, 1992 · O. Nasakin, A. N. Lyshchikov, P. M. Lukin

Chemistry of Heterocyclic Compounds

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Abstract

It was established that on treatment with alkali, 2,5-disubstituted 3,3,4,4-tetracyanopyrrolidines react with primary alcohols to form 5-alkoxy-2-(N-arylidenamino)-3,4-dicyanopyrroles. Depending on the ratio of the initial reagents, another reaction route is possible, leading to 6-alkoxy-4-amino-2-R-3-CH2R-5-cyano-3H-pyrrolo[2,3-d]pyrimidines. The effect of substituents on the reaction pathways is examined.

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2,5-disubstituted 3,3,4,4-tetracyanopyrrolidines react with primary alcohols to form 5-alkoxy-2-(N-arylidenamino)-3,4-dicyanopyrroles, with the reaction pathway influenced by substituents

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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Reactions of 3,3,4,4-tetracyanopyrrolidines with alcohols

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