Philip J Hamzik, Jason D Brubaker
2010
Citations
0
Influential Citations
35
Citations
Journal
Organic letters
Abstract
The oxetane ring is useful in drug discovery as a bioisostere for both the geminal dimethyl group and the carbonyl group. A convenient, straightforward approach to access structurally diverse 3-aminooxetanes through the reactivity of oxetan-3-tert-butylsulfinimine and the corresponding sulfinylaziridine is described.