Paper
Reactivity of Baccatin III Derivatives towards Samarium II reagents
Published Mar 6, 1995 · S. Py, F. Khuong-Huu
Tetrahedron Letters
Q3 SJR score
7
Citations
0
Influential Citations
Abstract
Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.
Study Snapshot
Baccatin III derivatives show efficient synthesis when exposed to samarium II reagents, leading to the synthesis of 9-dihydro-10-deacetylbaccatin III and 2-debenzoyl-9-dihydro-10-deacetyl-
PopulationOlder adults (50-71 years)
Sample size24
MethodsObservational
OutcomesBody Mass Index projections
ResultsSocial networks mitigate obesity in older groups.
Sign up to use Study Snapshot
Consensus is limited without an account. Create an account or sign in to get more searches and use the Study Snapshot.
Full text analysis coming soon...
References
Samarium diiodide-mediated deoxygenation of taxol: A one-step synthesis of 10-deacetoxytaxol
A single-step synthesis of 10-deacetoxytaxol, a potential ovarian cancer treatment, was achieved using samarium diiodide-mediated deoxygenation of taxol.
1994·31citations·Gunda Ingrid Georg et al.·Journal of Organic Chemistry
Journal of Organic Chemistry
A simple synthesis of 10-deacetoxytaxol derivatives
Samarium diiodide effectively removes the C-10 oxygen substituent in taxol derivatives, with the reaction halted by protecting the C-7 hydroxyl group.
1994·25citations·R. Holton et al.·Tetrahedron Letters
Tetrahedron Letters
The conversion of α- to β-hydroxy esters by a deoxygenation/condensation reaction promoted by samarium diiodide
This study demonstrates that samarium diiodide can effectively convert -hydroxy esters to -hydroxy esters by promoting deoxygenation and condensing reactions.
1992·10citations·E. Enholm et al.·Tetrahedron Letters
Tetrahedron Letters
Antileukemic alkaloids from Taxus wallichiana Zucc
Cephalomannine, a new antileukemic taxane alkaloid, has been isolated from Taxus wallichiana, a plant closely related to taxol, with potential therapeutic applications.
1981·140citations·R. W. Miller et al.·Journal of Organic Chemistry
Journal of Organic Chemistry
Citations
Palladium-Catalyzed Direct Arylation of C(sp(3))-H Bonds of α-Cyano Aliphatic Amides.
This study demonstrates a efficient method for synthesis of arylated -cyano amides, which can be converted to medicinally important,-dialkylated acid and -amino acid derivatives.
2015·46citations·M. Damoder Reddy et al.·The Journal of organic chemistry
The Journal of organic chemistry
Selective reductive transformations using samarium diiodide-water.
Samarium diiodide-water systems enable unprecedented selectivity and new reactions in reductive electron transfer reagents, offering new possibilities for chemical exploration.
2012·86citations·M. Szostak et al.·Chemical communications
Chemical communications
Conversion of Conjugated Enones into Enantiomerically Pure ‐Hydroxy Ketones or 1,3‐Diols – Samarium(II) Bromide Reductions of Protected ,‐Dihydroxy Ketones
Conjugated enones can be converted into enantiomerically pure -hydroxy ketones or 1,3-diols using samarium(II) bromide reductions, with varying degrees of diastereocontrol.
2010·15citations·Andreas Zoerb et al.·European Journal of Organic Chemistry
European Journal of Organic Chemistry
The chemistry of taxol and related taxoids.
Taxol, a cancer drug, was first isolated from Western Yew bark in the 1960s and developed into a successful treatment for ovarian and breast cancers.
2002·42citations·D. Kingston et al.·Fortschritte der Chemie organischer Naturstoffe = Progress in the chemistry of organic natural products. Progres dans la chimie des substances organiques naturelles
Fortschritte der Chemie organischer Naturstoffe = Progress in the chemistry of organic natural products. Progres dans la chimie des substances organiques naturelles