Suryakant B. Sapkal, K. Shelke, A. H. Kategaonkar
Jun 1, 2009
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0
Influential Citations
17
Citations
Journal
Green Chemistry Letters and Reviews
Abstract
Abstract Ammonium acetate plays a dual role for the solvent-free synthesis of 1,3-oxazine under neat heating at 60°C and under microwave irradiation with excellent yields. The synthetic strategy involved the formation of a Betti base which upon condensation with aromatic aldehydes gives the preferred oxazine ring. The present protocol contributes remarkable advantages, such as solvent- and catalyst-free reaction conditions, simple work-up procedures, shorter reaction times, and environmentally benign methodology.