Role of exercise in estrogen deficiency-induced sarcopenia

doi:10.12965/jer.2244004.002

Paper

Role of exercise in estrogen deficiency-induced sarcopenia

Published Feb 1, 2022 · Eun-Jeong Cho, Youngju Choi, Su-Jeen Jung

Journal of Exercise Rehabilitation

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14

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0

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Abstract

A decline in estrogen levels during menopause is associated with the loss of muscle mass and function, and it can accelerate sarcopenia. However, with the growing number of postmenopausal women due to the increase in life expectancy, the effects of estrogen on skeletal muscle are not completely understood. This article reviews the relationship between estrogen deficiency and skeletal muscle, its potential mechanisms, including those involving mitochondria, and the effects of exercise on estrogen deficiency-induced skeletal muscle impairment. In particular, mitochondrial dysfunction induced by estrogen deficiency accelerates sarcopenia via mitochondrial dynamics, mitophagy, and mitochondrial-mediated apoptosis. It is well known that exercise training is essential for health, including for the improvement of sarcopenia. This review highlights the importance of exercise training (aerobic and resistance exercise) as a therapeutic intervention against estrogen deficiency-induced sarcopenia.

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Study Snapshot

Exercise training (aerobic and resistance) is crucial for improving muscle function and preventing muscle loss in postmenopausal women with estrogen deficiency-induced sarcopenia.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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Role of exercise in estrogen deficiency-induced sarcopenia

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Citations

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