P. Huleatt, Sze Shiong Choo, Sheena Chua
Sep 1, 2008
Citations
0
Influential Citations
18
Citations
Journal
Tetrahedron Letters
Abstract
The synthesis of 3-, 4-, 7-bromo and 4,7-dibrominated 5,6-dihydroxyindole (DHI) and 5,6-dihydroxyindole-2-carboxylic acid (DHICA) derivatives is reported. Hemetsberger and Bartoli indole syntheses were investigated and expedient routes to the desired compounds were developed. These indoles are valuable substrates for elaboration using transition metal-mediated cross-coupling chemistry.