Paper
Ruthenium-Catalyzed Azide Alkyne Cycloaddition Reaction: Scope, Mechanism, and Applications.
Published Nov 18, 2016 · Johan R Johansson, T. Beke-Somfai, Anna Said Stålsmeden
Chemical reviews
Q1 SJR score
255
Citations
1
Influential Citations
Abstract
The ruthenium-catalyzed azide alkyne cycloaddition (RuAAC) affords 1,5-disubstituted 1,2,3-triazoles in one step and complements the more established copper-catalyzed reaction providing the 1,4-isomer. The RuAAC reaction has quickly found its way into the organic chemistry toolbox and found applications in many different areas, such as medicinal chemistry, polymer synthesis, organocatalysis, supramolecular chemistry, and the construction of electronic devices. This Review discusses the mechanism, scope, and applications of the RuAAC reaction, covering the literature from the last 10 years.
Literature Review
Highly CitedStudy Snapshot
The ruthenium-catalyzed azide alkyne cycloaddition (RuAAC) provides efficient, one-step synthesis of 1,2,3-triazoles, with applications in medicinal chemistry, polymer synthesis, organocatalysis, supramolecular chemistry,
PopulationOlder adults (50-71 years)
Sample size24
MethodsObservational
OutcomesBody Mass Index projections
ResultsSocial networks mitigate obesity in older groups.
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