Paper
Sodium Tetrafluoroborate as a New and Highly Efficient Catalyst for One‐Pot Synthesis of 3,4‐Dihydropyrimidin‐2(1H)‐Ones and Thiones
Published Apr 1, 2007 · B. P. Bandgar, V. T. Kamble, S. Bavikar
Journal of The Chinese Chemical Society
Q3 SJR score
11
Citations
0
Influential Citations
Abstract
Sodium tetrafluoroborate (NaBF 4 ) is found to catalyze the three component condensation of an aldehyde, 1,3-dicarbonyl compound and urea or thiourea to afford the corresponding 3,4-dihydropyrimidin-2(1H)-ones and thiones in high yields. This method is very useful for the synthesis of a wide range of 3,4-dihydropyrimidin-2(1H)-ones and thiones from aromatic, heterocyclic, α,β-unsaturated aldehydes and aliphatic aldehydes.
Study Snapshot
Sodium tetrafluoroborate (NaBF4) catalyzes the one-pot synthesis of 3,4-dihydropyrimidin-2(1H)-ones and thiones from various aldehydes, making it a useful method for synthesis of various compounds
PopulationOlder adults (50-71 years)
Sample size24
MethodsObservational
OutcomesBody Mass Index projections
ResultsSocial networks mitigate obesity in older groups.
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References
New environmentally friendly solvent free synthesis of dihydropyrimidinones catalysed by N-butyl-N,N-dimethyl-α-phenylethylammonium bromide☆
N-Butyl-N,N-dimethyl--phenylethylammonium bromide efficiently catalyzes the solvent-free synthesis of dihydropyrimidinones, offering a greener alternative to traditional methods.
2003·75citations·K. Rosi Reddy et al.·Tetrahedron Letters
Tetrahedron Letters
High regio- and stereoselective Barbier reaction of carbonyl compounds mediated by NaBF4/Zn (Sn) in water
NaBF4/Zn (Sn) in water facilitates the allylation of various carbonyl compounds, allowing for alternative - and -addition products of crotylations.
2003·26citations·Zhenggen Zha et al.·New Journal of Chemistry
New Journal of Chemistry
Vanadium(III) chloride catalyzed Biginelli condensation: solution phase library generation of dihydropyrimidin-(2H)-ones☆
The three-component condensation of aldehyde, -keto ester, and urea in the presence of vanadium(III) chloride allows for the efficient and quick parallel synthesis of dihydropyrimidinones in good yields.
2003·134citations·G. Sabitha et al.·Tetrahedron Letters
Tetrahedron Letters
Silica sulfuric acid: an efficient and reusable catalyst for the one-pot synthesis of 3,4-dihydropyrimidin-2(1H)-ones
Silica sulfuric acid efficiently catalyzes the Biginelli reaction to produce dihydropyrimidinones in high yields, making it a reusable catalyst for one-pot synthesis.
2003·295citations·P. Salehi et al.·Tetrahedron Letters
Tetrahedron Letters
Indium(III) bromide-catalyzed preparation of dihydropyrimidinones: improved protocol conditions for the Biginelli reaction
Indium(III) bromide-catalyzed Biginelli reaction produces excellent yields, allows for catalyst recycling, and leads to zero-discharge during the process.
2002·317citations·N. Fu et al.·Tetrahedron
Tetrahedron
Ionic liquids catalyzed Biginelli reaction under solvent-free conditions
Ionic liquids catalyze the Biginelli reaction under solvent-free conditions, resulting in high yields of 3,4-dihydropyrimidin-2(1H)-ones.
2001·295citations·Jiajian Peng et al.·Tetrahedron Letters
Tetrahedron Letters
Citations
In Melting Points We Trust: A Review on the Misguiding Characterization of Multicomponent Reactions Adducts and Intermediates
Using melting points to characterize multicomponent reactions' products and intermediates can be misleading and has misguided advances in organic synthesis.
2022·3citations·B. A. Neto et al.·Molecules
Molecules
INVESTIGATION OF SYNTHESIS PARAMETERS OF ANTIMONY FLUOROBORATE AND ITS USABILITY AS A FLAME RETARDANT FOR CELLULOSIC FABRICS
Antimony fluoroborate impregnation in cellulosic fabrics enhances their thermal stability and flame retardancy, making it a promising flame retardant for these materials.
2021·2citations·Duygu Aydin et al.·Cellulose Chemistry and Technology
Cellulose Chemistry and Technology
Preparation and Characterization of FeCo2O4 Nanoparticles: A Robust and Reusable Nanocatalyst for the Synthesis of 3,4-Dihydropyrimidin- 2(1H)-thiones and Thiazolopyrimidines
FeCo2O4 nanoparticles are a powerful and reusable catalyst for the synthesis of 3,4-dihydropyrimidine-2(1H)-thiones and thiazolopyrimidines, offering excellent yields and short reaction times.
2019·0citations·Farah Sadat Mousavi-Moghadam et al.·Current Nanoscience
Current Nanoscience
Novel synthesis of dihydropyrimidines for α-glucosidase inhibition to treat type 2 diabetes: in vitro biological evaluation and in silico docking.
The new method for synthesizing dihydropyrimidines shows potential for treating type 2 diabetes by inhibiting -glucosidase at low micro-molar concentrations.
2014·51citations·M. Yar et al.·Bioorganic chemistry
Bioorganic chemistry
Multi-component One-Pot Synthesis of 4-Aryl Substituted Dihydropyrimidinones and Mechanistic Study Under Solvent-Free Conditions Using NiO2 as Heterogeneous Recyclable Green Catalyst
Nickel oxide catalyst under solvent-free conditions and microwave irradiation leads to excellent yields and shorter product formation time in the synthesis of 3,4-dihydropyrimidin-2(1H)-one.
2013·6citations·Jaggi Lal et al.·Proceedings of the National Academy of Sciences, India Section A: Physical Sciences
Proceedings of the National Academy of Sciences, India Section A: Physical Sciences
Efficient and facile synthesis of heterocycles and their mechanistic consideration using kaolin
Kaolin catalyzed solvent-free synthesis of new heterocyclic compounds is a simple, clean, and efficient method for obtaining new compounds within minutes.
2013·26citations·P. Sahu et al.·RSC Advances
RSC Advances
One-Pot Synthesis of Dihydropyrimidine-Thione Derivatives Using Tungstate Sulfuric Acid (TSA) as a Recyclable Catalyst
Tungstate sulfuric acid (TSA) provides an efficient, environmentally benign, and environmentally friendly method for the one-pot synthesis of 3,4-dihydropyrimidine-2-(1H) thione derivatives under solvent-free conditions.
2012·19citations·B. Karami et al.·Phosphorus, Sulfur, and Silicon and the Related Elements
Phosphorus, Sulfur, and Silicon and the Related Elements
Three‐Component One‐Pot Synthesis of Indeno[2′,1′:5,6]Pyrido[2,3‐d]Pyrazole Derivatives in Aqueous Media
This study presents a three-component one-pot synthesis of indeno[2',1':5,6]pyrido[2,3-d]pyrazoles in aqueous media, demonstrating their potential as novel anti-inflammatory agents.
2009·14citations·D. Shi et al.·Journal of The Chinese Chemical Society
Journal of The Chinese Chemical Society