C. Sams, J. Lau
Dec 24, 1999
Citations
0
Influential Citations
9
Citations
Journal
Tetrahedron Letters
Abstract
The synthesis of 3,5-substituted 1,2,4-oxadiazoles on solid support is described. Benzoic acids bound to the Wang linker on a polystyrene resin are activated and allowed to react with N-hydroxyamidines. The resulting acylated N-hydroxyamidines are converted into 1,2,4-oxadiazoles at 125°C.