Gaoquan Chen, Jiao Chen, Chao Cheng
Apr 1, 2017
Citations
0
Influential Citations
9
Citations
Journal
Journal of Molecular Liquids
Abstract
Abstract Solubility of 2-amino-5-methylthiazole in methanol, ethanol, n -propanol, isopropanol, acetone, 2-butanone, acetonitrile, ethyl acetate, toluene, 1,4-dioxane and cyclohexane were determined by using the isothermal saturation method over a temperature range from (278.15 to 313.15) K under atmosphere pressure (101.2 kPa). The solubility of 2-amino-5-methylthiazole in the studied solvents increased with the increase in temperature, and the mole solubility obeyed the following order from high to low in different solvents: methanol > ethyl acetate > acetone > ethanol > 1,4-dioxane > (2-butanone, n -propanol) > isopropanol > acetonitrile > toluene > cyclohexane. The attained solubility data of 2-amino-5-methylthiazole were correlated by using the modified Apelblat equation, λh equation, Wilson model and NRTL model. The maximum values of root-mean-square deviation ( RMSD ) and relative average deviation ( RAD ) were 10.66 × 10 − 4 and 1.74%, respectively. Furthermore, the mixing Gibbs energy, mixing enthalpy, mixing entropy, activity coefficient at infinitesimal concentration and reduced excess enthalpy were evaluated.