Some nucleophilic substitution reactions of 2-chloro-3-cyanopyridines

doi:10.1007/BF00510110

Paper

Some nucleophilic substitution reactions of 2-chloro-3-cyanopyridines

Published Aug 1, 1976 · Z. A. Bomika, M. B. Andaburskaya, Yu. E. Pelcher

Chemistry of Heterocyclic Compounds

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3

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Abstract

The chlorine atom in 2-chloro-3-cyanopyridines is readily replaced by primary and secondary aliphatic amines and heterocyclic amines to give 2-aminopyridines. 2-Chloro-3-cyanopyridines react with hydrazine hydrate and sodium azide to give hydrazinopyridines, pyridopyrazoles, azidopyridines, and pyridotetrazoles.

Study Snapshot

2-chloro-3-cyanopyridines can be easily substituted with aliphatic amines and heterocyclic amines to produce 2-aminopyridines, and they react with hydrazine hydrate and sodium azide to produce hydrazinopyridines, pyri

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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Some nucleophilic substitution reactions of 2-chloro-3-cyanopyridines

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