The broad spectrum antiviral agent ribavirin inhibits capping of mRNA.

doi:10.1016/0006-291X(79)91853-9

Paper

The broad spectrum antiviral agent ribavirin inhibits capping of mRNA.

Published Aug 13, 1979 · Biswendu B. Goswami, Ernest Borek, Opendra K. Sharma

Biochemical and biophysical research communications

Q1 SJR score

211

Citations

5

Influential Citations

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Abstract

Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.

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Study Snapshot

Ribavirin is a broad-spectrum antiviral agent that inhibits capping of viral mRNA, potentially explaining its effectiveness against both DNA and RNA viruses but ineffective against polio virus.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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Paper

The broad spectrum antiviral agent ribavirin inhibits capping of mRNA.

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References

Citations

Effects on viral suppression and the early-immune expression of ribavirin against spring viremia of carp virus in vitro.

Ribavirin effectively inhibits early viral replication in carp cells, promoting early immune responses and potentially protecting against viral infections in fish.

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Ribavirin-poloxamer microparticles can enhance permeability across the nasal mucosa, potentially improving direct nose-to-brain transport for highly water-soluble drugs.

A review: Mechanism of action of antiviral drugs

Antiviral drugs target either the viruses themselves or host cell factors, with some effective treatments for herpes, influenza, and hepatitis C, but many more are needed.

Therapeutic drugs for SARS-CoV-2 treatment: Current state and perspective

Antiviral drugs, antibiotics, and immune-stimulant drugs are currently being tested for SARS-CoV-2 treatment, with potential for effective management with co-administration and monitoring protocols.

Carvacrol inhibits the excessive immune response induced by influenza virus A via suppressing viral replication and TLR/RLR pattern recognition.

Carvacrol, the main constituent in Mosla chinensis Maxim, shows potential as an alternative treatment for excessive immune response induced by influenza virus A infection.