Huang Xue-sun
2007
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Journal
Strait Pharmaceutical Journal
Abstract
OBJECTIVE To establish a method for the determination of cefoperazone sodium,and research the stability of cefoperazone sodium with the four common used liquid in clinical.METHODS The determination of cefoperazone sodium was measured by RP-HPLC,the appearance,color variety and pH were in the same time.RESULTS The appearance,color variety and pH of cefoperazone sodium change clearly at room temperature within 6h,but cefoperazone sodium with the glucose turned turbidity clearly after 12h.CONCLUSION Cefoperazone sodium was stable with the four liquid within 6h,but it must be used carefully with the glucose.