Structure and biosynthesis of harzianopyridone, an antifungal metabolite of Trichoderma harzianum

doi:10.1039/P19890001885

Paper

Structure and biosynthesis of harzianopyridone, an antifungal metabolite of Trichoderma harzianum

Published 1989 · J. M. Dickinson, J. Hanson, P. Hitchcock

Journal of The Chemical Society-perkin Transactions 1

UNKNOWN SJR score

58

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1

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Abstract

An antifungal metabolite of Trichoderma harzianum has been shown to be (E)-4-hydroxy-6,6-dimethoxy-3-(2-methyl-1-oxohex-4-enyl)pyridin-2-one. The incorporation of [1-13C]- and [1,2-13C2]-acetic acid and [Me-13C]methionine into harzianopyridone and the sites of labelling were established by n.m.r. methods. A low incorporation of [U-14C]aspartic acid was also observed.

Study Snapshot

Harzianopyridone, an antifungal metabolite from Trichoderma harzianum, is a complex metabolite with multiple incorporated acetic acid, methionine, and low incorporation of U-14C aspartic acid.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

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Structure and biosynthesis of harzianopyridone, an antifungal metabolite of Trichoderma harzianum

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