A. Cooper
1966
Citations
0
Influential Citations
15
Citations
Journal
Tetrahedron
Abstract
Abstract Crystals of fusidic acid methyl ester 3- p -bromobenzoate are monoclinic, space group P2 1 with unit cell dimensions a = 10·310 A, b = 7·935 A, c = 22·06 A, and β = 91°36′. Then intensities of 3,314 reflections, observed with copper Kα X radiation, were measured, partly photographically, partly on a linear diffractometer. The structure was solved from calculated three dimensional Patterson and electron density distributions and partly refined by least squares calculations. The atomic positions found establish the chemical structure of fusidic acid proposed by Godtfredsen and Arrigoni (compare preceding paper).