M. Kitazawa, M. Akahane, Y. Nakano
Apr 1, 1989
Citations
0
Influential Citations
3
Citations
Quality indicators
Journal
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan
Abstract
The derivatives of 3-[3-oxospiro[benzofuran-2(3H),1'-cyclopropan]-5-yl]acrylic acid were synthesized and tested for antiulcer activities. As a result, 1-[3-[3-oxospiro[benzofuran-2(3H),1'-cyclopropan]-5- yl]acryloyl]piperidine(3t) and 4-[3-[3-oxospiro[benzofuran-2(3H),1'-cyclopropan]-5- yl]acryloyl]morpholine(3u) exhibited potent antiulcer activities.